Molecular biomarkers in cardiac hypertrophy
نویسندگان
چکیده
منابع مشابه
Cardiac Biomarkers and Left Ventricular Hypertrophy in Asymptomatic Hemodialysis Patients
BACKGROUND Cardiac biomarkers are often elevated in dialysis patients showing the presence of left ventricular dysfunction. The aim of the study is to establish the plasma levels of high-sensitivity cardiac troponin T (hs TnT), precursor of B-natriuretic peptide (NT-proBNP) and high sensitivity C-reactive protein (hs CRP) and their relation to the presence of left ventricular hypertrophy (LVH) ...
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Cardiac hypertrophy is one of the main ways in which cardiomyocytes respond to mechanical and neurohormonal stimuli. It enables myocytes to increase their work output, which improves cardiac pump function. However, this compensatory mechanism can become overwhelmed by biomechanical stress, thereby resulting in heart failure, which is associated with high morbidity and mortality. The complex mol...
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Colorectal cancer (CRC) is amongst the most widespread cancers and is a most common cause of cancer associated mortality universally. Since previous decades, it has been cleared that CRC develops owing to the buildup of a series of genetic and epigenetic changes in the normal colonic epithelium. Regardless of the current development in surgery and therapies, overall survival of end stage CRC pa...
متن کاملNovel molecular targets in the treatment of cardiac hypertrophy.
Left ventricular hypertrophy represents the heart's response to increased biomechanical stress such as arterial hypertension or valvular heart disease. Cardiac hypertrophy has traditionally been considered a compensatory mechanism required to normalize wall tension and to maintain cardiac output. However, recent clinical studies as well as several animal models have shown that sustained cardiac...
متن کاملCarvacrol Ameliorates Pathological Cardiac Hypertrophy in Both In-vivo and In-vitro Models
Hypertension-induced left ventricular hypertrophy is the most important risk factor for heart failure. This study aimed at investigating the effects of monoterpenoid phenol, carvacrol, on myocardial hypertrophy using both in-vivo and in-vitro models. Male Wistar rats were divided into the control (Ctl), un-treated hypertrophy (H), and carvacrol-treated hypertrophy gro...
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ژورنال
عنوان ژورنال: Journal of Cellular and Molecular Medicine
سال: 2019
ISSN: 1582-1838
DOI: 10.1111/jcmm.14129